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1

The Art and Science of Total Synthesis at the Dawn of the Twenty-First Century

K. C. Nicolaou, Dionisios Vourloumis, Nicolas Winssinger, Phil S. Baran

Journal:

Angewandte Chemie International Edition

Year:

2000

Language:

english

File:

PDF, 2.84 MB

english, 2000

2

Total Synthesis of Epothilone A: The Olefin Metathesis Approach

Dr. Zhen Yang, Yun He, Dr. Dionisios Vourloumis, Dr. Hans Vallberg, Prof. Dr. K. C. Nicolaou

Journal:

Angewandte Chemie International Edition

Year:

1997

Language:

english

File:

PDF, 339 KB

english, 1997

3

Solid-phase synthesis of benzimidazole libraries biased for RNA targets

Dionisios Vourloumis, Masayuki Takahashi, Klaus B Simonsen, Benjamin K Ayida, Sofia Barluenga, Geoffrey C Winters, Thomas Hermann

Journal:

Tetrahedron Letters

Year:

2003

Language:

english

File:

PDF, 371 KB

english, 2003

4

Dietary flavonoids in cancer therapy and prevention: Substrates and inhibitors of cytochrome P450 CYP1 enzymes

Vasilis P. Androutsopoulos, Athanasios Papakyriakou, Dionisios Vourloumis, Aristidis M. Tsatsakis, Demetrios A. Spandidos

Journal:

Pharmacology & Therapeutics

Year:

2010

Language:

english

File:

PDF, 1.06 MB

english, 2010

5

Totalsynthese von Epothilon E und seitenkettenmodifizierten Epothilon-Analoga durch Stille-Kupplung

K. C. Nicolaou, Yun He, Frank Roschangar, N. Paul King, Dionisios Vourloumis, Tianhu Li

Journal:

Angewandte Chemie

Year:

1998

File:

PDF, 125 KB

1998

6

Chemie und Biologie der Epothilone

Kyriacos C. Nicolaou, Frank Roschangar, Dionisios Vourloumis

Journal:

Angewandte Chemie

Year:

1998

Language:

german

File:

PDF, 1.51 MB

german, 1998

7

Der Stand der Totalsynthese zu Beginn des 21. Jahrhunderts

K. C. Nicolaou, Dionisios Vourloumis, Nicolas Winssinger, Phil S. Baran

Journal:

Angewandte Chemie

Year:

2000

Language:

german

File:

PDF, 2.91 MB

german, 2000

8

Total Synthesis of Epothilone E and Analogues with Modified Side Chains through the Stille Coupling Reaction

K. C. Nicolaou, Yun He, Frank Roschangar, N. Paul King, Dionisios Vourloumis, Tianhu Li

Journal:

Angewandte Chemie International Edition

Year:

1998

Language:

english

File:

PDF, 129 KB

english, 1998

9

Synthesis and Biological Activity of Sarcodictyins

K. C. Nicolaou, Sanghee Kim, Jeffrey Pfefferkorn, Jinyou Xu, Takashi Ohshima, Seijiro Hosokawa, Dionisios Vourloumis, Tianhu Li

Journal:

Angewandte Chemie International Edition

Year:

1998

Language:

english

File:

PDF, 108 KB

english, 1998

10

Chemical Biology of Epothilones

K. C. Nicolaou, Frank Roschangar, Dionisios Vourloumis

Journal:

Angewandte Chemie International Edition

Year:

1998

Language:

english

File:

PDF, 1.49 MB

english, 1998

11

Novel Paromamine Derivatives Exploring Shallow-Groove Recognition of Ribosomal- Decoding-Site RNA

Klaus B. Simonsen, Benjamin K. Ayida, Dionisios Vourloumis, Masayuki Takahashi, Geoffrey C. Winters, Sofia Barluenga, Seema Qamar, Sarah Shandrick, Qiang Zhao, Thomas Hermann

Journal:

Year:

2002

Language:

english

File:

PDF, 205 KB

english, 2002

12

Durch Olefinmetathese zum Epothilongerüst

Prof. Dr. K. C. Nicolaou, Yun He, Dr. Dionisios Vourloumis, Dr. Hans Vallberg, Dr. Zhen Yang

Journal:

Angewandte Chemie

Year:

1996

File:

PDF, 349 KB

1996

13

Die Totalsynthese von Epothilon A: der Zugang durch Olefinmetathese

Dr. Zhen Yang, Yun He, Dr. Dionisios Vourloumis, Dr. Hans Vallberg, Prof. Dr. K. C. Nicolaou

Journal:

Angewandte Chemie

Year:

1997

File:

PDF, 315 KB

1997

14

Gezielt entworfene Epothilone: kombinatorische Synthese, Induktion der Tubulin-Polymerisation und cytotoxische Wirkung gegen taxolresistente Tumorzellen

Prof. Dr. Kyriacos Costa Nicolaou, Dr. Dionisios Vourloumis, Dr. Tianhu Li, Dr. Joaquin Pastor, Nicolas Winssinger, Yun He, Dr. Sacha Ninkovic, Dr. Francisco Sarabia, Dr. Hans Vallberg, Dr. Frank Rosc

Journal:

Angewandte Chemie

Year:

1997

Language:

german

File:

PDF, 728 KB

german, 1997

15

Totalsynthese von Eleutherobin

Prof. Dr. Kyriacos Costa Nicolaou, Dr. Floris Van Delft, Dr. Takashi Ohshima, Dr. Dionisios Vourloumis, Dr. Jinyou Xu, Dr. Seijiro Hosokawa, Jeffrey Pfefferkorn, Dr. Sanghee Kim, Dr. Tianhu Li

Journal:

Angewandte Chemie

Year:

1997

File:

PDF, 526 KB

1997

16

Monitoring Molecular Recognition of the Ribosomal Decoding Site

Sarah Shandrick, Qiang Zhao, Qing Han, Benjamin K. Ayida, Masayuki Takahashi, Geoffrey C. Winters, Klaus B. Simonsen, Dionisios Vourloumis, Thomas Hermann

Journal:

Angewandte Chemie

Year:

2004

Language:

english

File:

PDF, 206 KB

english, 2004

17

Molecular Recognition by Glycoside Pseudo Base Pairs and Triples in an Apramycin–RNA Complex

Qing Han, Qiang Zhao, Sarah Fish, Klaus B. Simonsen, Dionisios Vourloumis, Jamie M. Froelich, Daniel Wall, Thomas Hermann

Journal:

Angewandte Chemie

Year:

2005

Language:

english

File:

PDF, 569 KB

english, 2005

18

An Approach to Epothilones Based on Olefin Metathesis

Prof. Dr. K. C. Nicolaou, Yun He, Dr. Dionisios Vourloumis, Dr. Hans Vallberg, Dr. Zhen Yang

Journal:

Angewandte Chemie International Edition

Year:

1996

Language:

english

File:

PDF, 346 KB

english, 1996

19

Designed Epothilones: Combinatorial Synthesis, Tubulin Assembly Properties, abd Cytotoxic Action against Taxol-Resistant Tumor Cells

Prof. Dr. K. C. Nicolaou, Dr. Dionisios Vourloumis, Dr. Tianhu Li, Dr. Joaquin Pastor, Nicolas Winssinger, Yun He, Dr. Sacha Ninkovic, Dr. Francisco Sarabia, Dr. Hans Vallberg, Dr. Frank Roschangar, D

Journal:

Angewandte Chemie International Edition

Year:

1997

Language:

english

File:

PDF, 881 KB

english, 1997

20

Total Synthesis of Eleutherobin

Prof. Dr. K. C. Nicolaou, Dr. Floris van Delft, Dr. Takashi Ohshima, Dr. Dionisios Vourloumis, Dr. Jinyou Xu, Dr. Seijiro Hosokawa, Jeffrey Pfefferkorn, Dr. Sanghee Kim, Dr. Tianhu Li

Journal:

Angewandte Chemie International Edition

Year:

1997

Language:

english

File:

PDF, 848 KB

english, 1997

21

Monitoring Molecular Recognition of the Ribosomal Decoding Site

Sarah Shandrick, Qiang Zhao, Qing Han, Benjamin K. Ayida, Masayuki Takahashi, Geoffrey C. Winters, Klaus B. Simonsen, Dionisios Vourloumis, Thomas Hermann

Journal:

Angewandte Chemie International Edition

Year:

2004

Language:

english

File:

PDF, 207 KB

english, 2004

22

Molecular Recognition by Glycoside Pseudo Base Pairs and Triples in an Apramycin–RNA Complex

Qing Han, Qiang Zhao, Sarah Fish, Klaus B. Simonsen, Dionisios Vourloumis, Jamie M. Froelich, Daniel Wall, Thomas Hermann

Journal:

Angewandte Chemie International Edition

Year:

2005

Language:

english

File:

PDF, 568 KB

english, 2005

23

Piperidine Glycosides Targeting the Ribosomal Decoding Site

Klaus B. Simonsen, Benjamin K. Ayida, Dionisios Vourloumis, Geoffrey C. Winters, Masayuki Takahashi, Sarah Shandrick, Qiang Zhao, Thomas Hermann

Journal:

Year:

2003

Language:

english

File:

PDF, 186 KB

english, 2003

24

Novel Acyclic Deoxystreptamine Mimetics Targeting the Ribosomal Decoding Site

Dionisios Vourloumis, Geoffrey C. Winters, Masayuki Takahashi, Klaus B. Simonsen, Benjamin K. Ayida, Sarah Shandrick, Qiang Zhao, Thomas Hermann

Journal:

Year:

2003

Language:

english

File:

PDF, 232 KB

english, 2003

25

Aminoglycoside-Hybrid Ligands Targeting the Ribosomal Decoding Site

Dionisios Vourloumis, Geoffrey C. Winters, Klaus B. Simonsen, Masayuki Takahashi, Benjamin K. Ayida, Sarah Shandrick, Qiang Zhao, Qing Han, Thomas Hermann

Journal:

Year:

2005

Language:

english

File:

PDF, 283 KB

english, 2005

26

Unnatural Rigid Scaffolds Targeting the Bacterial Ribosome

Ioannis A. Katsoulis, Constantina Pyrkotis, Athanasios Papakyriakou, Georgia Kythreoti, Alexandros L. Zografos, Ioannis Mavridis, Victoria R. Nahmias, Panoula Anastasopoulou, Dionisios Vourloumis

Journal:

Year:

2009

Language:

english

File:

PDF, 602 KB

english, 2009

27

Total Synthesis of Oxazole- and Cyclopropane-Containing Epothilone A Analogues by the Olefin Metathesis Approach

Prof. Dr. K. C. Nicolaou, Dr. Hans Vallberg, Dr. N. Paul King, Dr. Frank Roschangar, Yun He, Dr. Dionisios Vourloumis, Christopher G. Nicolaou

Journal:

Chemistry - A European Journal

Year:

1997

Language:

english

File:

PDF, 2.37 MB

english, 1997

28

Total Synthesis of Oxazole- and Cyclopropane-Containing Epothilone B Analogues by the Macrolactonization Approach

Prof. Dr. K. C. Nicolaou, Dr. Francisco Sarabia, Dr. M. Ray V. Finlay, Dr. Sacha Ninkovic, Dr. N. Paul King, Dr. Dionisios Vourloumis, Yun He

Journal:

Chemistry - A European Journal

Year:

1997

Language:

english

File:

PDF, 2.13 MB

english, 1997

29

ChemInform Abstract: Total Synthesis and Chemical Biology of the Sarcodictyins

K. C. Nicolaou, Jeffrey Pfefferkorn, Jinyou Xu, Nicolas Winssinger, Takashi Ohshima, Sanghee Kim, Seijiro Hosokawa, Dionisios Vourloumis, Floris van Delft, Tianhu Li

Journal:

Year:

2000

File:

PDF, 24 KB

2000

30

ChemInform Abstract: The Art and Science of Total Synthesis and the Dawn of the Twenty-First Century

K. C. Nicolaou, Dionisios Vourloumis, Nicolas Winssinger, Phil S. Baran

Journal:

Year:

2000

File:

PDF, 24 KB

2000

31

Novel Paromamine Derivatives Exploring Shallow-Groove Recognition of Ribosomal-Decoding-Site RNA.

Klaus B. Simonsen, Benjamin K. Ayida, Dionisios Vourloumis, Masayuki Takahashi, Geoffrey C. Winters, Sofia Barluenga, Seema Qamar, Sarah Shandrick, Qiang Zhao, Thomas Hermann

Journal:

Year:

2003

File:

PDF, 53 KB

2003

32

Novel 2,5-Dideoxystreptamine Derivatives Targeting the Ribosomal Decoding Site RNA.

Dionisios Vourloumis, Masayuki Takahashi, Geoffrey C. Winters, Klaus B. Simonsen, Benjamin K. Ayida, Sofia Barluenga, Seema Qamar, Sarah Shandrick, Qiang Zhao, Thomas Hermann

Journal:

Year:

2003

File:

PDF, 160 KB

2003

33

Total Synthesis of Apoptolidin: Completion of the Synthesis and Analogue Synthesis and Evaluation.

K. C. Nicolaou, Yiwei Li, Kazuyuki Sugita, Holger Monenschein, Prasuna Guntupalli, Helen J. Mitchell, Konstantina C. Fylaktakidou, Dionisios Vourloumis, Paraskevi Giannakakou, Aurora O'Brate

Journal:

Year:

2004

File:

PDF, 50 KB

2004

34

Discovery of Potent Vascular Endothelial Growth Factor Receptor-2 Inhibitors

Athanasios Papakyriakou, Maria E. Katsarou, Maria Belimezi, Michael Karpusas, Dionisios Vourloumis

Journal:

Year:

2010

Language:

english

File:

PDF, 802 KB

english, 2010

35

Rational design of azepane-glycoside antibiotics targeting the bacterial ribosome

Sofia Barluenga, Klaus B. Simonsen, Ethel S. Littlefield, Benjamin K. Ayida, Dionisios Vourloumis, Geoffrey C. Winters, Masayuki Takahashi, Sarah Shandrick, Qiang Zhao, Qing Han, Thomas Hermann

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 275 KB

english, 2004

36

Synthesis and characterization of novel natural product-Gd(III) MRI contrast agent conjugates

Eleni K. Efthimiadou, Maria E. Katsarou, Michael Fardis, Christos Zikos, Emmanuel N. Pitsinos, Athanasios Kazantzis, Leondios Leondiadis, Marina Sagnou, Dionisios Vourloumis

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 206 KB

english, 2008

37

A Homo sapiens cytoplasmic ribosomal decoding A-site affinity screen evaluating aminoglycoside and analogue binding

Georgia Kythreoti, Dionisios Vourloumis

Journal:

Analytical Biochemistry

Year:

2011

Language:

english

File:

PDF, 715 KB

english, 2011

38

Synthesis of dehydroalanine fragments as thiostrepton side chain mimetics

Benjamin K. Ayida, Klaus B. Simonsen, Dionisios Vourloumis, Thomas Hermann

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2005

Language:

english

File:

PDF, 124 KB

english, 2005

39

Second generation analogs of rigid 6,7-spiro scaffolds targeting the bacterial ribosome

Christos I. Stathakis, Ioannis Mavridis, Georgia Kythreoti, Athanasios Papakyriakou, Ioannis A. Katsoulis, Thomas Cottin, Panoula Anastasopoulou, Dionisios Vourloumis

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 695 KB

english, 2010

40

Novel generation of conjugated alkynyl ketenes: Efficient synthesis of β,γ-alkynyl lactones

Plato A. Magriotis, Dionisios Vourloumis, Mary E. Scott, Anna Tarli

Journal:

Tetrahedron Letters

Year:

1993

Language:

english

File:

PDF, 325 KB

english, 1993

41

Novel 2,5-dideoxystreptamine derivatives targeting the ribosomal decoding site RNA

Dionisios Vourloumis, Masayuki Takahashi, Geoffrey C Winters, Klaus B Simonsen, Benjamin K Ayida, Sofia Barluenga, Seema Qamar, Sarah Shandrick, Qiang Zhao, Thomas Hermann

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2002

Language:

english

File:

PDF, 258 KB

english, 2002

42

Synthesis and biological properties of C12,13-cyclopropylepothilone A and related epothilones

K.C. Nicolaou, M.Ray V. Finlay, Sacha Ninkovic, N.Paul King, Yun He, Tianhu Li, Francisco Sarabia, Dionisios Vourloumis

Journal:

Chemistry & Biology

Year:

1998

Language:

english

File:

PDF, 1.38 MB

english, 1998

43

Conformational dynamics of the EGFR kinase domain reveals structural features involved in activation

Athanasios Papakyriakou, Dionisios Vourloumis, Fotini Tzortzatou-Stathopoulou, Michael Karpusas

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2009

Language:

english

File:

PDF, 450 KB

english, 2009

44

Antitumor efficacy of 26-fluoroepothilone B against human prostate cancer xenografts

Robert A. Newman, Jun Yang, Raymond M. Finlay, Fernando Cabral, Dionisios Vourloumis, Clifton L. Stephens, Patricia Troncoso, Xiaobing Wu, Christopher J. Logothetis, K. Nicolaou, Nora M. Navone

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2001

Language:

english

File:

PDF, 260 KB

english, 2001

45

Comparative CYP1A1 and CYP1B1 substrate and inhibitor profile of dietary flavonoids

Vasilis P. Androutsopoulos, Athanasios Papakyriakou, Dionisios Vourloumis, Demetrios A. Spandidos

Journal:

Bioorganic & Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 893 KB

english, 2011

46

The Coral-Derived Natural Products Eleutherobin and Sarcodictyins A and B: Effects on the Assembly of Purified Tubulin with and without Microtubule-Associated Proteins and Binding at the Polymer Taxoid Site

Hamel, Ernest, Sackett, Dan L., Vourloumis, Dionisios, Nicolaou, K. C.

Journal:

Year:

1999

Language:

english

File:

PDF, 149 KB

english, 1999

47

Total Synthesis of Apoptolidin: Completion of the Synthesis and Analogue Synthesis and Evaluation

Nicolaou, K. C., Li, Yiwei, Sugita, Kazuyuki, Monenschein, Holger, Guntupalli, Prasuna, Mitchell, Helen J., Fylaktakidou, Konstantina C., Vourloumis, Dionisios, Giannakakou, Paraskevi, O'Brate, Aurora

Journal:

Journal of the American Chemical Society

Year:

2003

Language:

english

File:

PDF, 670 KB

english, 2003

48

Novel Copper(II) Complex of N -Propyl-norfloxacin and 1,10-Phenanthroline with Enhanced Antileukemic and DNA Nuclease Activities

Katsarou, Maria E., Efthimiadou, Eleni K., Psomas, George, Karaliota, Alexandra, Vourloumis, Dionisios

Journal:

Journal of Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 717 KB

english, 2008

49

Novel selective inhibitors of aminopeptidases that generate antigenic peptides

Papakyriakou, Athanasios, Zervoudi, Efthalia, Theodorakis, Emmanuel A., Saveanu, Loredana, Stratikos, Efstratios, Vourloumis, Dionisios

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2013

Language:

english

File:

PDF, 878 KB

english, 2013

50

Rigid spiroethers targeting the decoding center of the bacterial ribosome

Mavridis, Ioannis, Kythreoti, Georgia, Koltsida, Konstantina, Vourloumis, Dionisios

Journal:

Bioorganic & Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 1.27 MB

english, 2014